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Zovirax salbe rezeptfrei . Lysergic acid diethylamide (LSD) and its metabolites were studied by using the human hepatic microsomal microsatellite assay (HMASMA). This is sensitive enough and specific to detect the presence of active LSD (5-Hydroxy-Lysergic acid diethylamide (5-HIAA)) in urine most people but is not sensitive enough to distinguish between LSD and metabolite. The microsatellite assay was used to test all three metabolites of LSD (d 5-HIAA vs. 5-HIAA/d 5-HIAA; dl 5-HO-DET 5-HO-DET; and LSD-5-HIAA vs. LSD-5-HIAA) based on data from a study done in humans (Friedman, 1979). The 3,4-methylenedioxymethamphetamine (MDMA) metabolite was also tested in the same microsatellite assay with no significant differences between the two groups (Table ). presence of the LSD metabolite in urine was determined by the analysis of its metabolites (5-HIAA/d LSD-5-HIAA vs. LSD-5-HIAA/d LSD-5-HIAA) using the U.S. Pharmacopeia formula. These data are summarized in Table where LSD and LSD-5-HIAA were generic zovirax cost found in all three categories. These results show that the 3,4-methylenedioxymethamphetamine (MDMA) metabolite is not active when measured in a microsatellite assay to detect LSD; however, it does remain active in some tests. TABLE 2. Methylenedioxy Methamphetamine (MDE) Methylenedioxymethamphetamine (MDMA) LSD No. (%) mg L−1 mmol Open in a separate window B. Laboratory Diagnostic Tests Are Not Specific for LSD and LSD-5-HIAA in Humans The human U.S. Pharmacopeia (USP) formula states that dl L-5-hydroxy-Lysergic acid diethylamide (5-HIAA), 5-hydroxy-DET, and dl LSD-5-HIAA are inactive when measured in microsatellite (1M) assay to detect LSD in humans. Although no studies have been done to test laboratory diagnostic tests for LSD in humans, they have been used in zovirax cold sore cream price animals where their analytical efficiency and specificity have been measured. The USP has used for in vitro tests other psychedelics, such as 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) in rats (Levine, 1989). All three studies have found that in vitro tests for L-5-hydroxy-Lysergic acid diethylamide (LSD)-related metabolites (5-HIAA, 5-HIAA/d 5-HIAA vs. LSD-5-HIAA/d LSD-5-HIAA), however, do not distinguish between LSD and metabolites. The same tests using USP formula have been used to test pharmacy online usa viagra urine samples for LSD (Table ) with no significant differences between the two groups. Finally, a study using the test formula also failed to demonstrate any significant differences in the test results between LSD and LSD-5-HIAA (Levine, 1989). Because of these studies, in addition to clinical symptoms of LSD and LSD-5-HIAA which mimic symptoms of the illness, laboratory examination urine samples has only been used to identify the drug in some clinical populations. For instance, research has shown that the laboratory test for L-5-hydroxy-Lysergic acid diethylamide (LSD) is a useful tool to screen blood samples for the presence of LSD-like drug (Hoffman et al., 1988). It has also been found that the test is sensitive enough to identify LSD and LSD-related compounds in blood samples (Lundberg et al., 1988; O'Neil and Smith, 1989). However, because urine is often less sensitive than blood, it is important to note that it does not differentiate between LSD and metabolites. Thus, although some laboratories use this test to screen for LSD in urine samples to detect LSD and metabolites, it cannot differentiate between LSD and LSD-related compounds. The reason that laboratory diagnostic tests are not specifically useful for LSD and LSD-5-HIAA is that both types of drugs can interfere with the lab diagnostic test. For example, LSD may alter analytical stability of the laboratory diagnostic test kits (see the)